Übersicht unserer Publikationen

  • Dreyer AK, Hoffmann D, Lachmann N, Ackermann M, Steinemann D, Timm B, Siler U, Reichenbach J, Grez M, Moritz T, Schambach A, Cathomen T. 2015. TALEN-mediated functional correction of X-linked chronic granulomatous disease in patient-derived induced pluripotent stem cells. Biomaterials 69:191-200.
  • Rahman S. H., J. Kuehle, C. Reimann, T. Mlambo, J. Alzubi, M. L. Maeder, H. Riedel, P. Fisch, T. Cantz, C. Rudolph, C. Mussolino, J. K. Joung, A. Schambach, and T. Cathomen. 2015. Rescue of DNA-PK Signaling and T-Cell Differentiation by Targeted Genome Editing in a prkdc Deficient iPSC Disease Model. PLoS Genet 11(5):e1005239.
  • Schott J. W., N. M. Jaeschke, D. Hoffmann, T. Maetzig, M. Ballmaier, T. Godinho, T. Cathomen, and A. Schambach. 2015. Deciphering the impact of parameters influencing transgene expression kinetics after repeated cell transduction with integration-deficient retroviral vectors. Cytometry A 87:405-18.
  • Hacein-Bey-Abina S., S. Y. Pai, H. B. Gaspar, M. Armant, C. C. Berry, S. Blanche, J. Bleesing, J. Blondeau, H. de Boer, K. F. Buckland, L. Caccavelli, G. Cros, S. De Oliveira, K. S. Fernández, D. Guo, C. E. Harris, G. Hopkins, L. E. Lehmann, A. Lim, W. B. London, J. C. van der Loo, N. Malani, F. Male, P. Malik, M. A. Marinovic, A. M. McNicol, D. Moshous, B. Neven, M. Oleastro, C. Picard, J. Ritz, C. Rivat, A. Schambach, K. L. Shaw, E. A. Sherman, L. E. Silberstein, E. Six, F. Touzot, A. Tsytsykova, J. Xu-Bayford, C. Baum, F. D. Bushman, A. Fischer, D. B. Kohn, A. H. Filipovich, L. D. Notarangelo, M. Cavazzana, D. A. Williams, and A. J. Thrasher. A modified γ-retrovirus vector for X-linked severe combined immunodeficiency. N Engl J Med 371:1407-17.
  • Doudna J. A., and E. Charpentier 2014. Genome editing. The new frontier of genome engineering with CRISPR-Cas9. Science 346(6213):1258096.
  • Schott J. W., D. Hoffmann, T. Maetzig, F. J. Müller, D. Steinemann, D. Zychlinski, T. Cantz, C. Baum, and A. Schambach. 2014. Improved retroviral episome transfer of transcription factors enables sustained cell fate modification. Gene Ther 21:938-49.
  • Bobis-Wozowicz S., M. Galla, J. Alzubi, J. Kuehle, C. Baum, A. Schambach, and T. Cathomen. 2014. Non-integrating gamma-retroviral vectors as a versatile tool for transient zinc-finger nuclease delivery. Sci Rep 4:4656.
  • Maetzig T., J. Kuehle, A. Schwarzer, S. Turan, M. Rothe, A. Chaturvedi, M. Morgan, T. C. Ha, M. Heuser, W. Hammerschmidt, C. Baum, and A. Schambach. 2014. All-in-One inducible lentiviral vector systems based on drug controlled FLP recombinase. Biomaterials 35:4345-56.
  • Kuehle J., S. Turan, T. Cantz, D. Hoffmann, J. D. Suerth, T. Maetzig, D. Zychlinski, C. Klein, D. Steinemann, C. Baum, J. Bode, and A. Schambach. 2014. Modified lentiviral LTRs allow Flp recombinase-mediated cassette exchange and in vivo tracing of "factor-free" induced pluripotent stem cells. Mol Ther 22:919-28.
  • Rahman S.H., S. Bobis-Wozowicz, D. Chatterjee, K. Gellhaus, K. Pars, R. Heilbronn, R. Jacobs, and T. Cathomen. 2013. The nontoxic cell cycle modulator indirubin augments transduction of adeno-associated viral vectors and zinc-finger nuclease-mediated gene targeting. Hum Gene Ther 24:67-77.
  • Suerth J. D., T. Maetzig, M. H. Brugman, N. Heinz, J. U. Appelt, K. B. Kaufmann, M. Schmidt, M. Grez, U. Modlich, C. Baum, and A. Schambach. 2012. Alpharetroviral self-inactivating vectors: long-term transgene expression in murine hematopoietic cells and low genotoxicity. Mol Ther 20:1022-32.
  • Jinek, M., K. Chylinski, I. Fonfara, M. Hauer, J. A. Doudna, and E. Charpentier. 2012. A programmable dual-RNA guided DNA endonuclease in adaptive bacterial immunity. Science 337:816-821.
  • Warlich E., J. Kuehle, T. Cantz, M. H. Brugman, T. Maetzig, M. Galla, A. A. Filipczyk, S. Halle, H. Klump, H. R. Schöler, C. Baum, T. Schroeder, and A. Schambach. 2011. Lentiviral vector design and imaging approaches to visualize the early stages of cellular reprogramming. Mol Ther 19:782-9.
  • Maetzig T., M. H. Brugman, S. Bartels, N. Heinz, O. S. Kustikova, U. Modlich, Z. Li, M. Galla, B. Schiedlmeier, A. Schambach*, and C. Baum. Polyclonal fluctuation of lentiviral vector-transduced and expanded murine hematopoietic stem cells. Blood 2011; 117:3053-64. * co-corresponding.
  • Deltcheva, E., K. Chylinski, C. Sharma, and E. Charpentier. 2011. CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III. 2011. Nature 471:602-607. ”