Übersicht unserer Publikationen

  • Hoseini SS, Hapke M, Herbst J, Wedekind D, Baumann R, Krueger A, Heinz N, Schiedlmeier B, Vignali D, van den Brink MRM, Schambach A, Blazar BR, Sauer MG. Inducible T-cell receptor expression in precursor T-cells for leukemia control. Leukemia 2015 Jul;29(7):1530-1542.

  • Hoseini SS and Sauer MG. Molecular cloning using polymerase chain reaction, an educational guide for cellular engineering. J Biol Engineering. 2015 Jan 19;9:2.

  • Beier R, Maecker-Kolhoff  B, Sykora KW, Chao M, Kratz C, Sauer MG. Minimal antileukaemic treatment followed by reduced-intensity conditioning in three consecutive children with Fanconi anemia and AML. Bone Marrow Transplant. 2015, Mar;50(3):463-4.

  • Ghosh A, Holland AM, Dogan Y, Yim, N, Rao U, Young LF, West M, Singer N, Hae Lee, Na IK Jennifer Tsai J, Jenq R, Penack O, Hanash A, Murphy G, Liu C, Sadelain M, Sauer M, Sant'Angelo D, van den Brink M. PLZF confers effector functions on donor T cells leading to enhanced graft-versus-tumor effects. Cancer Res 2013, Aug 1;73(15):4687-4696.

  • Ghosh A, Dogan Y, Moroz M, Holland A, Yim N, Rao U, Young L, Tannenbaum D, Masih D, Velardi E, Tsai J, Jenq R, Penack O, Hanash A, Smith O, Piersanti K, Lezcano C, Murphy G, Liu C, Palomba ML, Sauer M, Sadelain M, Ponomarev V, van den Brink M. Fratricidal TRAIL+T cells eliminate alloactivated T cells and augment anti-tumor activity after bone marrow transplantation. JCI 2013 Jun 3;123(6):2654-62.

  • Beier R, MH Albert, P Bader, A Borkhardt, U Creutzig, M Eyrich, B Gruhn, J Greil, R Handgretinger, W Holter, B Kremens, P Lang, I Müller, C Mauz-Körholz, R Meisel, C Peters, R Reinhardt, C Rössig, P Sedlacek, A Schulz, F Schuster, A Schrauder, B Strahm, KW Sykora, W Wössmann, M Zimmermann, M Sauer. Allogeneic stem cell transplantation using busulfan, cyclophosphamide, and melphalan for children with acute myeloid leukemia in second complete remission. Bone Marrow Transplant. 2013 April;48(4):491-501.

  • Beier R, Schulz A, Hönig M, Eyrich M, Schlegel PG, Holter W, Stachel KD, Ehlert K, Greil J, Nürnberger W, Wößmann W,  Bader P, Urban C, Müller I, Suttorp M, Sauer M, Gruhn B, Meisel R, Zimmermann M, Sykora KW. Longterm follow up with children conditioned with Tresosulfan: German and Austrian experience. Bone Marrow Transplant. 2013 Apr;48(4):491-501.

  • Rajendra J, Feldmann V, Koestner W, Gottschalk S, Kardinal C, Mayer HA, Sauer M, Engelmann J. Multifunctional silica nanoparticles for optical and magnetic resonance imaging. Biol. Chem. 2012 August;394(1):125-135.

  • Kotlarz D, Beier R, Murugan D, Diestelhorst J, Jensen O, Boztug K, Pfeifer D, Kreipe H, ED Pfister, Baumann U, Puchalka J, Bohne J, Egritas O, Dalgic B, Kolho KL, Sauerbrey A, Buderus S, Güngör T, Enninger A, Koda YKL, Guariso G, Batia Weiss B, Corbacioglu S, Socha P, Metin UN, Wahbeh GT, Husain K, Ramadan D, Al-Herz W,  Grimbacher B, Sauer M, Sykora KW, Koletzko S, and Klein C. Loss of Interleukin-10 Signaling and Infantile Inflammatory Bowel Disease - Implications for Diagnosis and Therapy. Gastroenterology 2012 Aug;143(2):347-55.

  • Kempf T, Zarbock A, Widera C, Butz S, Stadtmann A, Rossaint J, Bolomini-Vittori M, Korf-Klingebiel M, Napp LC, Hansen B, Kanwischer A, Bavendiek U, Beutel G, Hapke M, Sauer MG, Laudanna C, Hogg N, Vestweber D, Wollert KC. GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice. Nat Med. 2011 May;17(5):581-8.

  • Keliris A, Ziegler T, Mishra R, Pohmann R, Sauer M, Ugurbil K, Engelmann J. Synthesis and characterization of a cell-permeable bimodal contrast agent targeting β-galactosidase. Bioorg. Med. Chem. 2011 Apr 15;19(8):2529-40.

  • Koestner W, Hapke M, J Herbst, Klein C, Welte K, Frueauf J, Flatley A, Vignali D, Blazar BR, Sauer M. PD-L1 blockade effectively restores strong graft-versus-leukemia effects without graft-versus-host-disease after delayed adoptive transfer of T-cell receptor gene-engineered allogeneic CD8+ T cells. Blood. 2011 Jan 20;117(3):1030-41.

  • Glockner EO, Kotlarz D, Boztug K, Gertz M, Schäffer AA, Noyan F, Perro M, Diestelhorst J, Allroth A, Murugan D, Hätscher N, Pfeifer D, Sykora KW, Sauer M, Kreipe H, Lacher M, Nustede R, Woellner C, Baumann U, Salzer U, Koletzko S, Shah N, Segal A, Sauerbrey A, Buderus S, Snapper S, Grimmbacher B, Klein C. Early onset inflammatory bowel disease caused by IL 10 Receptor Mutations. N Engl J Med. 2009 Nov 19;361(21):2033-45.

  • Mishra R, Su W, Pohmann R, Pfeuffer J, Sauer M, Ugurbil K, Engelmann J. Cell-penetrating peptides and peptide nucleic acid-coupled MRI contrast agents: Evaluation of cellular delivery and target binding. Bioconjugate Chem. 2009, 20, 1860–1868.

  • Dahl D, Koenecke C, Hahn A, Heuft HG, Dammann E, Stadler M, Buchholz S, Krauter J, Eder M, Sykora KW, Klein C, Ganser A, Sauer M. Prolonged isolated red cell transfusion requirement after allogeneic blood stem cell transplantation: Identification of patients at risk. Transfusion. 2010 Mar;50(3):649-55.

  • Ghosh A, Koestner W, Hapke M, Länger F, Baumann R, Könecke C, Welte K, Blazar BR, Sauer M. In vitro priming of donor T cells on host-derived antigen presenting cells can mediate strong graft versus leukemia effects without graft versus host disease after MHC disparate bone marrow transplantation.Blood. 2009 Apr 30;113(18):4440-8.

  • Meissner B, Fuchs D, Gruhn B, Kabisch H, Erttmann R, Suttorp M, Beilken A, Luecke T, Welte K, Grigull L, Sykora KW, Sauer M. Allogeneic blood stem cell transplantation for children with Hurler’s syndrome: Results from the German multi center approach MPS-SCT 2005. Bone Marrow Transplant. 2009 Mar;43(5):375-81.

  • Maecker B, Meissner B, Bettoni da Cunha-Riehm C, Sauer M, Welte K, Sykora KW. Severe graft failure presumably due to phenytoin-induced hypersensitivity syndrome in two patients after bone marrow transplantation. Bone Marrow Transplant. 2008 May;41(9):833-5.

  • Ghosh A, Wolenski M, Klein C, Welte K, Blazar BR, and Sauer M. Cytotoxic T cells reactive to an immunodominant leukemia-associated antigen can be specifically primed and expanded by combining a specific priming step with non specific large- scale expansion.J Immunother. 2008 Feb-Mar;31(2):121-31.

  • Meissner B, Borkhardt A, Dilloo, Fuchs D, Friedrich W, Handgretinger R, Peters C,  Schrauder A, Schuster F, Vormoor J, Maecker B, Sykora KW, Zintl F,  Welte K, Sauer M. Relapse, not regimen-related toxicity was the major cause of treatment failure in eleven children with Down syndrome undergoing haematopoietic stem cell transplantation for acute leukemia. Bone Marrow Transplant. 2007 Nov;40(10):945-9.

  • Sauer M, Zeidler C, Meissner B, Rehe K, Hanke A, Welte K, Lohse P, Sykora KW. Substitution of cyclophosphamide and busulfan by fludarabine, treosulfan and melphalan in a preparative regimen for children and adolescents with Shwachman-Diamond syndrome. Bone Marrow Transplant. 2007 Feb;39(3):143-7.

  • Rathinam C, Sauer M, Ghosh A, Rudolph C, Hegazy A, Schlegelberger B, Welte K, Klein C. Generation and characterization of a novel hematopietic progenitor cell line with DC differentiation potential. Leukemia. 2006 May;20(5):870-6.

  • Sauer M, Bettoni C, Lauten M, Ghosh A, Rehe K, Grigull L, et al. Complete substitution of cyclophosphamide by fludarabine and ATG in a busulfan-based preparative regimen for children and adolescents with beta-thalassemia. Bone Marrow Transplant 2005;36(5):383-7.

  • Steward C, Blair A, Moppet J, Clarke E, Virgo P, Lankester A, Burger S, Sauer M, Flanagan A, Pamphilon D, Orchard P. High peripheral blood progenitor cell counts enable autologous back-up before stem cell transplantation for malignant infantile osteopetrosis. Biol Blood Marrow Transplant. 2005;11(2):115-21.

  • Sauer M, Ericson M, Weigel B, Herron M, Angela Panoskaltisis-Mortari, Kren B, Levine B, Serody J, June C, Taylor P, Blazar B. A novel system for simultaneous tracking and biological assessment of leukaemia cells and leukaemia-reactive cytotoxic T-cells (CTLs). Cancer Res 64(11):3914-212 (2004).